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1.
Arq. neuropsiquiatr ; 62(2b): 414-420, jun. 2004. tab, graf
Article in English | LILACS | ID: lil-362204

ABSTRACT

Trinta casos de poliomielite associada à vacinação oral (Sabin) foram estudados a partir de 4081 notificações de paralisias agudas e flácidas feitas ao Ministério da Saúde no período de 1989 a 1995, com o objetivo de avaliar a gravidade do quadro neurológico. Dezesseis pacientes tiveram monoplegia, 6 paraplegia, 5 tetraplegia, 2 hemiplegia e 1 triplegia. Foram 56% em menores de 1 ano, 56,7% no sexo feminino, 46% dos casos provenientes do nordeste. Em 10 pacientes foi isolado o vírus vacinal P2, em oito o P3 e dois o P1. Os demais tinham associações de mais de um tipo de vírus. Febre antes ou após o período prodrômico e o uso de medicação intramuscular não se relacionaram a maior morbidade. A política antipoliomielite adotada no Brasil levou à erradicação da poliomielite pelo vírus selvagem com um risco mínimo do ponto de vista epidemiológico, porém ainda com custos individuais não desprezíveis.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Paralysis/chemically induced , Poliomyelitis/chemically induced , Poliovirus Vaccine, Oral/adverse effects , Brazil/epidemiology , Cost-Benefit Analysis , Morbidity , Paralysis/epidemiology , Paralysis/virology , Poliomyelitis/epidemiology , Poliomyelitis/virology , Risk Factors
2.
Arq. neuropsiquiatr ; 60(2B): 367-373, June 2002. tab, graf
Article in English | LILACS | ID: lil-310852

ABSTRACT

To know the impact of the Guillain Barréá³yndrome (GBS) in the population less than 15 years old, after the eradication of poliomyelitis. Data bank from the program of epidemiological surveillance of acute flaccid palsies (AFP) from the Funda礯 Nacional de Saåáúere analyzed between 1990 -- 1996. From 3619 notifications of AFP there were 1678 GBS. GBS yearly incidence rates is 0.39-0.63 cases/100,000. No consistent seasonal variation existed or relationship to vaccines. Weakness at inclusion were, moderate 52.1 percent, severe in 47.9 percent, sixty days after 57.1 percent normal, 7.4 percent mild, 15.7 percent moderate, 10.4 percent with severe deficits, death in 5.4 percent. 67 (4.0 percent) cases unknown. Death rates varies from 2.8 percent in southeast to 7.9 percent in the northeast. GBS was the most frequent cause of AFP. In spite of the severity of this disease being similar in the different regions, the outcome varies according to origin of the cases, possibly reflecting the economical conditions in those places


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Guillain-Barre Syndrome/epidemiology , Poliovirus Vaccine, Oral , Age Distribution , Brazil , Follow-Up Studies , Guillain-Barre Syndrome/chemically induced , Incidence , Poliomyelitis , Prognosis , Seasons , Sex Distribution
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